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What Is TriMix Testosterone?

TriMix is a prescription form of erectile injection prescribed for men with symptoms of impotence. It is used to treat men with ED or Erectile Dysfunction, hypogonadism, Andropause or low testosterone. TriMix is made up of an injectable compound that includes a combination of three injections in a single dose - Phentolamine Mesylate, Papaverine Hydrochloride and Prostaglandin E1 for injection. TriMix Therapy is also known as Triple P and is very effective as an intercavernosal injection for erectile dysfunction. The therapy uses three vasoactive agents, papaverine, phentolamine, and prostaglandin E1 (PGE1 alprostadil), also used in Caverject®, Edex®, Viridal®. This combination of androgens is common in testosterone replacement therapy, but this particular form of it is specifically formulated to treat impotence. TriMix is approved by the FDA and is an innovative solution featuring a long-acting androgen steroid shot to address erectile dysfunction issues in men of all ages.


Why use TriMix Injections?

TriMix is a great erectile solution when oral impotence treatment pills like Viagra, Cialis and Levitra are no longer effective treatment options. Trimix can be prescribed along with other androgen treatment on the market for use with other testosterone replacement therapy options, as it offers new and exciting possibilities when it comes to combining therapies to effectively treat erectile dysfunction. Most testosterone injection compounds require at least one, if not several, injections per week like TriMix. Similar to the P-Shot® or Priupus injection, the Trimix compound is taken by injection directly into the penile shaft resulting in an erection, and with the ability for the man to have more erections for up to 24 hours. ED physicians and Urologists usually prescribe TriMix for ED symptoms in 3 weekly injections. An autoinjector pen and gel solution is also available.


How to Use TriMix as a TRT Treatment

TriMix must be prescribed and either self-administered or administered by a trained healthcare professional in a licensed medical clinic or office. You must have a prescription from your doctor in order to buy and use TriMix. A testosterone blood test and physical examination will assist your physician with providing a proper diagnoses and formulation of an effective androgen treatment program. You will receive a single shot in your buttock. Because of certain risks associated with TriMix (namely POME and anaphylaxis), you will need to remain at the clinic after you receive your shot to be sure you have no serious reactions to the injection. TriMix® is indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone.


TriMix Therapy Instructions

TriMix Dosing and Administration Schedule

TriMix can be prescribed to treat Erectile Dysfunction Caused by Hypogonadism (Low T) with 2 to 3 shots per week. A typical dose of TriMix is papaverine 30 mg, phentolamine 1 mg, and prostaglandin E1 (PGE-1) 10 mcg per 1 ml, or a BiMix of papaverine 30 mg and phentolamine 1 mg depending upon the patients age and condition. The dosing schedule is as follows:
  • Initial Injection - 2.5 mcg
  • Initial Injection - up to 10 mcg for men over 65
  • Second Injection if needed up to 2.5 mcg
  • 24 Hour Intervals with increments of 5 to 10 mcg not to exceed 40mcg if needed to acieve erection.

The Initial dosage as recommended for Edex® and Caverject Impulse® is 2.5 mcg with a second dose of 2.5 mcg if the initial dose is insufficient. TriMix dosage can be increased by 5 to 10 mcg at each additional attempt depending upon the erectile response with each dose not to exceed total of 40 mcg. Higher doses for intracavernosal injections like TriMix are needed in older men age 65 to 85 in order to achieve erections. It is not uncommon for an initial dose of 10 mcg to be used for men who are over the of 65.

How TriMix works?

The three P's in Trimix help create an erection by relaxing the smooth muscles and widening the blood vessels in the penis. Trimix Injections using a combination of the three erectile injections in a single dose should begin to work within 5-20 minutes, and its effects should last about 30 minutes to an 1 hour or two. Most men should be able to naturally have an erection for about 24 hours after TriMix administration. The different erectile products are available separately in lower strengths than that found in the Trimix Injection. For most men, using .5cc of TriMix should give good results and in many cases the erection may last too long well or in excess of 2 hours and the dosage to may then be dropped to .45 cc or lower. Alprostadil Injection is a prostaglandin (PGE-1). It works by relaxing certain muscles in the penis and widening blood vessels, which increases blood flow to the penis and helps to cause an erection. When the effect of the alprostadil wears off, blood flow returns to normal and the erection disappears. Phentolamine shots are given by injection causing penile blood vessels to expand increasing blood flow. When injected into the penis intracavernosally, it increases blood flow to the penis resulting in an erection. Papaverine is a penile vasodilator that relaxes smooth muscles in your blood vessels to help them dilate or widen. This lowers blood pressure and allows blood to flow more easily through your penile veins and arteries. Papaverine is used to treat many conditions such as erectile dysfunction in men and health conditions that cause spasm of smooth muscle.

Risks & Possible Side Effects of TriMix

TriMix® has been reported to be safe and effective. For over two decades it has been prescibed for men with impotence, and TriMix self-injection therapy has proven to be both safe and effective. It is considered the best second-line drug therapy for the management of erectile dysfunction by Urologists, ED Physicians and Endocrinologists. However as with all prescription medications there are risks and side effects. Fibrotic reactions with intracavernous injection therapy have been observed. A variety of reactions, ranging from subcutaneous nodules, intracavernosal fibrotic areas, penile plaques, lumps, swelling, tenderness, or curving have been reported. For this reason, routine clinical follow-ups are used to help identify fibrosis or new fibrosis, and PGE1 causes less fibrosis than the other drugs used for ED. Any penile nodules, lumps or swelling that occur with TriMix injection therapy disappear within a few months of stopping.

The 3 vasoactive agents commonly used alone or in combination are papaverine, phentolamine, and prostaglandin E1 (PGE1 alprostadil). Some men have sensitivities which could cause penile pain, headaches, dizziness, bruising at the injections site, and prolonged erections. The ED product should not be used by men with anatomical deformation of the penis or with penile implants.

How to Inject TriMix

  • If you have an Autoinjector like Caverject®, a premeasured does will be able to be set and easily injected.
  • For those with a traditional vial, place your TriMix medication vial, syringes, and alcohol swabs on a clean surface.
  • Wash hands with soap and water. Wipe the top of the vial with the alcohol swab.
  • Remove the syringe from its package, attach the needle and pull off the cap.
  • Pull on the plunger until an amount of air is in the syringe equal to the amount of medication you will be injecting. Insert the needle into the rubber stopper at the top of the vial and push in the air.
  • Turn the vial and syringe upside down and draw up the recommended dosage into the syringe. Tap the syringe gently and push gently on the plunger to remove air bubbles.
  • Sitting upright, hold the head of your penis stretching it lengthwise. Inject the medication into the corpora cavernosa which is the spongy tissue on the sides at the base of your penis. Some men massage the area for a few seconds after injection.
  • Clean the injection site with a fresh alcohol swab.
  • Where and How to buy TriMix Injections?

    You can order TriMix Injections and testosterone from a licensed medical practitioner, Endocrinologist or ED Physician. Contact us to find a TriMix certified physician who trained in the administration and precautions of using TriMix for their patients. If for any reason you are not a good candidate for ED Therapy with TriMix, then the other testosterone replacement options may be more suitable. You can read more about Enanthate Injections Online and Cypionate Injections Online, get info about Propionate Injections Online.


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    How much does TriMix cost?

    ED related procedures can cost from $400 to over $2,000 depending upon the treatment. Injection of Corpora Cavernosa with Pharmacologic Agents is in the range of $400 to $600 depending upon the prescription of TriMix.


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    Chemical formula: C19H28O2
    Drug class: Androgen (Anabolic Steroid)
    Treatment: Hypogonadism (Andropause), Delayed puberty, ED (Erectile Dysfunction), Breast Neoplasm
    Typical Trimix Dosage using Titration: 2.5 to 50 mcg Prostaglandine (Alprostadil), 30 mg Papaverine, 1mg to 1.5 mg Phentolamine; Prefilled Autoinjectors .6ml
    Administration: Testosterone is an IM shot (injected into a muscle) Weekly, bi-weekly or monthly. Daily as a cream, gel, patch or pill. 3 to 5 months as an implantable pellet. Side effects: Headache, Acne, Increased facial or body hair, Increased sex drive, Redness at injection site, Swelling, Numbness, Itching, Rash, Aggression or Anxiety
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    These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. No claim or opinion on the HGH.BZ website is intended to be nor should it be construed to be medical advice or hormone diagnosis. Please consult with a healthcare professional before starting any therapeutic program including HRT - Hormone Replacement Therapy.




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